Don't bother with the drivers on their website, which are outdated. Go to FTDI, the company that makes the chip inside. They have up-to-date drivers even for intel Macs.
To talk to your serial device, you could get goSerial, but I wanted to do some on-the-fly analysis using python (of course). For this, I use pyserial. You just have to make sure that you link to the serial device correctly, as the FTDI drivers call it something nonstandard.
For example, here is a little script that uses pyserial to echo serial mouse output:
import serial
ser = serial.Serial('/dev/cu.usbserial-A5001uBe', 1200, \
bytesize=7, parity='N', stopbits=1)
while 1:
c1 = ser.read()
c2 = ser.read()
c3 = ser.read()
print oct(ord(c1)), oct(ord(c2)), oct(ord(c3))
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